Microbial enzyme secretion

Microbial enzyme secretion

Identification of secretion systems in bacterial genomes http://www.nature.com/articles/srep23080 This relatively recent publication deals with computational methods for identifying secretion system genes in genomic sequences. Bacterial secretion systems review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804464/ This review is on bacterial secretion systems with a major focus on their role in...

Secretin and pancreatic enzyme secretion.

Microbial Secretion via ESETEC(R) Technology

The success of biopharmaceuticals started about 30 years ago with the first production of recombinant human insulin (Humulin®) in Escherichia coli, followed by the first production of human tissue plasminogen activator (tPA) in mammalian host cells some years later. Due to the lack of glycosylation in E. coli, which is required for the biological activity of most monoclonal antibodies, the use ...

Chemistry of enzyme inhibitors of microbial origin.

Study of antibiotics has furnished interesting materials to chemistry of natural products. I initiated the screening study of enzyme inhibitors produced by microorganisms and isolated leupeptin and antipain inhibiting trypsin and papain, chymostatin inhibiting chymotrypsin, pepstatin inhibiting pepsin, panosialin inhibiting sialidases, oudenone inhibiting tyrosine hydroxylase, dopastin inhibiti...

Fungal morphogenesis and enzyme secretion during pathogenesis

Fungi represent a highly diverse evolutionary group of eukaryotic, heterotrophic organisms which share a common cellular organisation. The fungill thallus or mycelium consists of hyph<le, tubular slructures which may be divided into cellular units by sepIa. Growth of fungal hyph;lC occurs al thc lip and is medialed by continuous synthesis aIIII scnction of cell w;i11 material to the apex. Hypha...